Fertility Preservation Options after Gonadotoxic Chemotherapy

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Fertility Preservation Options After Gonadotoxic Chemotherapy

Chemotherapy has the potential to deplete and destroy a woman's reproductive potential. Although many oncologists are referring women for fertility preservation before chemotherapy, in many cases there is limited time for fertility preservation. This review provides an overview of the impact of cancer and chemotherapy on the ovarian reserve, a summary of methods of fertility preservation prior ...

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Male fertility preservation before gonadotoxic therapies

BACKGROUND Recent advances in cancer therapy have resulted in an increased number of long-term cancer survivors. Unfortunately, aggressive chemotherapy, radiotherapy and preparative regimens for bone marrow transplantation can severely affect male germ cells, including spermatogonial stem cells (SSCs), and lead to permanent loss of fertility. Different options for fertility preservation are dep...

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Strategies for fertility preservation and gonadal protection during gonadotoxic chemotherapy and radiotherapy

With the recent report of a pregnancy and delivery after autotransplantation of cryopreserved-thawed ovarian cortical strips, preservation of the reproductive potential resurfaced. There is a growing academic and public interest in exploring the available strategies for fertility preservation in patients at risk. This is due to the increasing incidence of cancer during the reproductive age. The...

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Fertility preservation in women with malignant tumors and gonadotoxic treatments.

BACKGROUND Because of improved survival rates and recent advances in reproductive medicine, fertility preservation methods in women of reproductive age with malignant or autoimmune diseases have risen in importance. METHODS Selective literature review based on the authors' clinical and scientific experience. RESULTS Fertility-preserving techniques are recommended for all girls and women up ...

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ژورنال

عنوان ژورنال: Clinical Medicine Insights: Reproductive Health

سال: 2013

ISSN: 1179-5581,1179-5581

DOI: 10.4137/cmrh.s10848